Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus
| Terminal Bus Palermo | Brindisi Bus Stop | CheapestFastest |
Last refresh of the prices: Yesterday at 5:18 AM CEST.
Get from Palermo to Brindisi
The journey takes about 11 hours 45 minutes, and with fares starting at just CLP 58,813, it presents an excellent value for a comfortable ride.
Bus stations and stops in Palermo and Brindisi
Stops in Palermo
- A
Terminal Bus Palermo
Via Tommaso Fazello, 16, 90123 Palermo PA, Italy - B
Palermo Airport
Punta Raisi, 90145, Palermo - C
Piazza Cairoli
Piazza Cairoli, 8-14, 90123 Palermo, Italy - D
Fiera
90143 Palermo PA, Italy - E
Via Paolo Balsamo, 31
Via Paolo Balsamo, 23-31, 90123 Palermo, Italy - F
Piazza Ruggero Settimo, 12
Piazza Ruggero Settimo, 12C, 90139 Palermo, Italy
Stops in Brindisi
- A
Brindisi Bus Stop
Via Giuseppe Maria Galanti, 8, 72100 Brindisi BR, Italy - C
Fermata dell'autobus Brindisi
Viale Arno, 72100 Brindisi BR, Italy - D
Porto
Viale Regina Margherita, 72100 Brindisi BR, Italy - E
Brindisi Rione Casale
Via Osanna, 97, 72100 Brindisi BR, Italy - F
Via Palmiro Togliatti
Via Palmiro Togliatti, 11, 72100 Brindisi BR, Italy
Compare bus companies
Based on 15882 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi‑Fi. FlixBus ticket prices on this trip start at CLP 58,813
Frequently asked questions about travelling from Palermo to Brindisi by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Palermo to Brindisi?
The cheapest bus tickets from Palermo to Brindisi start from CLP 58,813. The average price for this route is around CLP 71,176. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Palermo to Brindisi?
The average bus travel time from Palermo to Brindisi is 11h 45m, covering a distance of 482 km. The quickest bus can get you there in 11h 45m and is operated by FlixBus.
Which bus companies service the Palermo to Brindisi route?
Several major bus companies operate on this route with 1 buses available per day.
What are the earliest and latest departure times for the bus from Palermo to Brindisi?
The earliest bus departs from Palermo to Brindisi at 6:15pm. And the latest bus departs at 9:10pm.
What are the CO₂ emissions for the bus trip from Palermo to Brindisi?
A bus trip from Palermo to Brindisi generates an estimated 12.041274999999999 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Palermo to Brindisi was searched and found on Sep 24, 2026 with a price of CLP 72,135To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Palermo to Brindisi, as early as possible.
You can expect to pay from CLP 72,135 to CLP 80,901 for a bus ticket from Palermo to Brindisi based on the last 2 days. You can expect to find the cheapest price for the trip at CLP 80,901 which is on 2026-09-26.
