Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus
| Parcheggio Via Pietransantina | Lampugnano bus station | Cheapest | ||||
| Bus
| park Aurelia | Milan (Assago M2) | Fastest | ||||
| Bus
| park Aurelia | Milan (Malpensa Airport Terminal 1) | No tags | ||||
| Bus
| park Aurelia | Aeroporto Malpensa T2 | No tags | ||||
| Bus
| Parcheggio Via Pietransantina | Milan (Malpensa Airport Terminal 1) | No tags | ||||
| Bus
| Parcheggio Via Pietransantina | Milan (Malpensa Airport Terminal 1) | No tags | ||||
| Bus
| Parcheggio Via Pietransantina | Aeroporto Malpensa T2 | No tags | ||||
| Bus
| Parcheggio Via Pietransantina | Aeroporto Malpensa T2 | No tags |
Last refresh of the prices: Yesterday at 10:00 PM CEST.
Compare 2 ways to go from Pisa to Milano
Among the sustainable travel choices, the Bus stands out as a good way to reach Milano. The journey takes about 6 hours, and with fares starting at just CLP 16,424, it presents an excellent value for a comfortable ride.
Bus stations and stops in Pisa and Milano
Stops in Pisa
- A
Parcheggio Via Pietransantina
Via Pietrasantina, 56123 Pisa PI - C
Piazza della Stazione, 10
Piazza della Stazione, 10, 56125 Pisa PI, Italy - D
Piazza della Stazione
Piazza della Stazione, 1, 56125 Pisa PI, Italy
Stops in Milano
- B
Piazza I Maggio, 1
Piazza I Maggio, 1, 20099 Sesto San Giovanni MI, Italy - C
Lampugnano
Via Giulio Natta, 228, 20151 Milano, Italy - E
Milan San Donato Bus Station
Via Giuseppe Impastato, 27, 20138 Milano, Italy - F
Molino Dorino
Molino Dorino, 20151 Milano, Italy
Compare bus companies
Based on 16022 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi‑Fi. FlixBus ticket prices on this trip start at CLP 16,424
Frequently asked questions about travelling from Pisa to Milano by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Pisa to Milano?
The cheapest bus tickets from Pisa to Milano start from CLP 16,424. The average price for this route is around CLP 39,196. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Pisa to Milano?
The average bus travel time from Pisa to Milano is 6h, covering a distance of 226 km. The quickest bus can get you there in 4h 35m and is operated by FlixBus.
Which bus companies service the Pisa to Milano route?
Several major bus companies operate on this route with 18 buses available per day.
What are the earliest and latest departure times for the bus from Pisa to Milano?
The earliest bus departs from Pisa to Milano at 4:45am. And the latest bus departs at 11:30pm.
What are the CO₂ emissions for the bus trip from Pisa to Milano?
A bus trip from Pisa to Milano generates an estimated 5.639099999999999 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Pisa to Milano was searched and found on Oct 8, 2026 with a price of CLP 19,319To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pisa to Milano, as early as possible.
You can expect to pay from CLP 19,319 to CLP 131,827 for a bus ticket from Pisa to Milano based on the last 2 days. You can expect to find the cheapest price for the trip at CLP 19,319 which is on 2026-10-08.
