Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus
| Rome Tiburtina Bus Station | Brindisi Bus Stop | Cheapest | ||||
| Bus
| Rome Tiburtina Bus Station | Brindisi Bus Stop | Fastest | ||||
 | Bus
| Rome Tiburtina Bus Station | Brindisi Bus Stop | No tags | ||||
 | Bus
| Rome Tiburtina Bus Station | Brindisi Bus Stop | No tags | ||||
| Bus
| Aeroporto Ciampino Airport (CIA) | Brindisi Bus Stop | No tags | ||||
| Bus
| Rome Tiburtina Bus Station | Brindisi Bus Stop | No tags | ||||
| Bus
| Rome Tiburtina Bus Station | Brindisi Bus Stop | No tags | ||||
| Bus
| Aeroporto Ciampino Airport (CIA) | Brindisi Bus Stop | No tags |
Last refresh of the prices: Yesterday at 8:24 PM CEST.
Get from Rome to Brindisi
The journey takes about 8 hours 25 minutes, and with fares starting at just ARS 14,940, it presents an excellent value for a comfortable ride.
Bus stations and stops in Rome and Brindisi
Stops in Rome
- C
Rome Tiburtina Bus Station
Largo Guido Mazzoni, 3, 00162 Roma, Italy - D
Castro Pretorio
Viale Castro Pretorio 76, 00185 Roma, Italy - E
Roma
- F
Anagnina
Via Vincenzo Giudice, 00173 Roma RM, Italy
Stops in Brindisi
- A
Brindisi Bus Stop
Via Giuseppe Maria Galanti, 8, 72100 Brindisi BR, Italy - C
Fermata dell'autobus Brindisi
Viale Arno, 72100 Brindisi BR, Italy - D
Porto
Viale Regina Margherita, 72100 Brindisi BR, Italy - E
Brindisi Rione Casale
Via Osanna, 97, 72100 Brindisi BR, Italy - F
Via Palmiro Togliatti
Via Palmiro Togliatti, 11, 72100 Brindisi BR, Italy
Compare bus companies
Frequently asked questions about travelling from Rome to Brindisi by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Rome to Brindisi?
The cheapest bus tickets from Rome to Brindisi start from ARS 14,940. The average price for this route is around ARS 50,507. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Rome to Brindisi?
The average bus travel time from Rome to Brindisi is 8h 25m, covering a distance of 479 km. The quickest bus can get you there in 7h 25m and is operated by FlixBus.
Which bus companies service the Rome to Brindisi route?
What are the earliest and latest departure times for the bus from Rome to Brindisi?
The earliest bus departs from Rome to Brindisi at 3:05am. And the latest bus departs at 11:55pm.
What are the CO₂ emissions for the bus trip from Rome to Brindisi?
A bus trip from Rome to Brindisi generates an estimated 11.9635 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Rome to Brindisi?
According to Busbud customers, the highest-rated bus company on this route is MarinoBus, with an average rating of 4.1 out of 5 stars based on 980 reviews.
Which bus company has the best Wi-Fi from Rome to Brindisi?
Based on Busbud reviews, the bus company MarinoBus has the highest Wi-Fi rating with a score of 3.5.
Which bus company has the best on-time performance from Rome to Brindisi?
According to Busbud traveller reviews, the most punctual bus company on this route is MarinoBus, with a punctuality rating of 4.3 out of 5 stars.
Which bus company has the cleanest buses from Rome to Brindisi?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is MarinoBus, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Rome to Brindisi was searched and found on Oct 2, 2026 with a price of ARS 14,409To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rome to Brindisi, as early as possible.
You can expect to pay from ARS 14,409 to ARS 150,255 for a bus ticket from Rome to Brindisi based on the last 2 days. You can expect to find the cheapest price for the trip at ARS 17,112 which is on 2026-10-06.
What's the cheapest way to go from Rome to Brindisi?
The Bus is the cheapest travel choice for this destination
