Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Price and booking link |
|---|---|---|---|---|---|---|---|
FlixBus + Greyhound | Bus
| Worcester Union Station | Florence, SC | ||||
FlixBus + Greyhound | Bus
| Worcester Union Station | Florence, SC | ||||
 | Bus
| Worcester Union Station | Bus station | ||||
FlixBus + Greyhound | Bus
| Worcester Union Station | Bus station | ||||
Greyhound + FlixBus | Bus
| Worcester Union Station | Florence, SC |
Get from Worcester to Florence
The journey takes about 21 hours 20 minutes, and with fares starting at just $150, it presents an excellent value for a comfortable ride.
Bus stations and stops in Worcester and Florence
Stops in Worcester
- A
Union Station
2 Washington Sq, Worcester, MA 01604 - B
146 P&R
530 Southwest Cutoff (Commuter service only), Millbury, MA 01527
Stops in Florence
- A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA - B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Compare bus companies
Based on 88208 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi‑Fi. Greyhound ticket prices on this trip start at $150
Greyhound Worcester Florence recent customer reviews
Ty for all the help
Nathaniel N.
Frequently asked questions about travelling from Worcester, US to Florence, SC, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Worcester to Florence?
The cheapest bus tickets from Worcester to Florence start from $150. The average price for this route is around $177. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Worcester to Florence?
The average bus travel time from Worcester to Florence is 21h 20m, covering a distance of 1135 km. The quickest bus can get you there in 19h 30m and is operated by Greyhound.
Which bus companies service the Worcester to Florence route?
Several major bus companies operate on this route with 2 buses available per day.
What are the earliest and latest departure times for the bus from Worcester to Florence?
The earliest bus departs from Worcester to Florence at 8:25am. And the latest bus departs at 4:35pm.
What are the CO₂ emissions for the bus trip from Worcester to Florence?
A bus trip from Worcester to Florence generates an estimated 28.36335 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Worcester, US to Florence, SC, US was searched and found on Oct 9, 2026 with a price of $141To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Worcester, US to Florence, SC, US, as early as possible.
You can expect to pay from $141 to $141 for a bus ticket from Worcester, US to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $141 which is on 2026-10-09.
