Next departures from Brussels to Prague on 6 October
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Wi‑Fi
Toilet
Power outlets
Brussels North Train Station
Prague (Main Railway Station)
Cheapest
Bus
Wi‑Fi
Toilet
Power outlets
Brussels North Train Station
Prague (Central Bus Station Florenc)
Fastest
Bus
Wi‑Fi
Toilet
Power outlets
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Brussels North Train Station
Prague (Main Railway Station)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Brussels North Train Station
Prague (Main Railway Station)
No tags
Next departures from Brussels to Prague on 8 October
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Toilet
Power outlets
Brussels South (Gare du Midi)
Florenc
CheapestFastest
Next departures from Brussels to Prague on 9 October
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Brussels North Train Station
Florenc
Cheapest
Bus
Brussels-South (Gare du Midi)
Florenc
Fastest
Next departures from Brussels to Prague on 10 October
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Wi‑Fi
Toilet
Power outlets
Brussels North Train Station
Prague (Na Knížecí)
Cheapest
Bus
Wi‑Fi
Toilet
Power outlets
Brussels North Train Station
Prague (Central Bus Station Florenc)
Fastest
Bus
Wi‑Fi
Toilet
Power outlets
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Brussels North Train Station
Prague (Main Railway Station)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Brussels North Train Station
Prague (Main Railway Station)
No tags
Next departures from Brussels to Prague on 11 October
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Toilet
Power outlets
Brussels South (Gare du Midi)
Florenc
CheapestFastest
Bus
Wi‑Fi
Toilet
Power outlets
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Brussels North Train Station
Prague (Main Railway Station)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Brussels North Train Station
Prague (Main Railway Station)
No tags
Next departures from Brussels to Prague on 13 October
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Wi‑Fi
Toilet
Power outlets
Brussels North Train Station
Prague (Na Knížecí)
Cheapest
Bus
Wi‑Fi
Toilet
Power outlets
Brussels North Train Station
Prague (Central Bus Station Florenc)
Fastest
Bus
Wi‑Fi
Toilet
Power outlets
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Brussels North Train Station
Prague (Main Railway Station)
No tags
Bus
Wi‑Fi
Toilet
Power outlets
Brussels North Train Station
Prague (Main Railway Station)
No tags
Last refresh of the prices: Today at 05:23 CEST.
Compare 2 ways to travel from Brussels to Prague
We recommend taking the bus
Among the sustainable travel choices, the Bus stands out as a good way to reach Prague. The journey takes about 18 hours 35 minutes and with fares starting at just £20, it presents an excellent value for a comfortable ride.
Based on 16076 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi‑Fi. FlixBus ticket prices on this trip start at £20
Based on 12956 reviews, the company was rated 3.7 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the Wi‑Fi. BlaBlaCar Bus ticket prices on this trip start at £51
Based on 1115 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the departure location and the ticket access but often complained with the Wi‑Fi. RegioJet ticket prices on this trip start at £34
RegioJet Brussels Prague recent customer reviews
RegioJet is the best bus
Every Thing was nice
Very good
Frequently asked questions about travelling by bus from Brussels to Prague
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Brussels to Prague?
The cheapest coach tickets from Brussels to Prague start from £20. The average price for this route is around £53. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Brussels to Prague?
The average bus journey time from Brussels to Prague is 18h 35m, covering a distance of 442 miles. The fastest bus can take you there in 11h 55m and is operated by RegioJet.
Which bus companies service the Brussels to Prague route?
Several major bus companies operate on this route with 36 buses available per day, including services from FlixBus, BlaBlaCar Bus, RegioJet.
What is the earliest and latest departure time for the bus from Brussels to Prague?
The earliest bus departs from Brussels to Prague at 00:45. And the latest bus departs at 22:55.
What are the CO₂ emissions for the bus trip from Brussels to Prague?
A bus journey from Brussels to Prague produces an estimated 17.8137 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Brussels to Prague?
According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1112 reviews.
Which company has the best Wi-Fi from Brussels to Prague?
Based on Busbud reviews, the bus company RegioJet has the best Wi-Fi rating with a score of 3.7.
Which bus company offers the most punctual service from Brussels to Prague?
According to Busbud traveller reviews, the most punctual bus company on this route is RegioJet, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Brussels to Prague?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.3 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
04/10
£46
05/10
£56
Today
£46
07/10
No data
08/10
£36
09/10
£51
10/10
£48
11/10
£45
The cheapest trip from Brussels to Prague was searched and found on 8 Oct 2026 with a price of £36
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Brussels to Prague as early as possible.
You can expect to pay from £36 to £130 for a bus ticket from Brussels to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at £36, which is on 2026-10-08.
What's the cheapest way to go from Brussels to Prague?
The Bus is the cheapest travel choice for this destination
The cheapest trip from Brussels to Prague was searched and found on 8 Oct 2026 with a price of £36
The Bus is the cheapest travel choice for this destination
