Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Plzeň Autobusová Zastávka | Brussels South (Gare du Midi) | CheapestFastest |
Last refresh of the prices: Last Wednesday at 23:25 CEST.
Compare 2 ways to travel from Plzeň to Brussels
Among the sustainable travel choices, the Bus stands out as a good way to reach Brussels. The journey takes about 17 hours 40 minutes and with fares starting at just €54, it presents an excellent value for a comfortable ride.
Where are the popular stops in Plzeň and Brussels?
Stops in Plzeň
- ARokycanská 1171/6, Lobzy 301 00 Plzeň-Plzeň 4, Czech Republic
- BHusova 2713/60, 301 00 Plzeň 3, Czech Republic
- C
nám. Republiky 358/33
nám. Republiky 358/33, Vnitřní Město, 301 00 Plzeň-Plzeň 3, Czech Republic - D
Rokycanská 1328/112
Rokycanská 1328/112, Doubravka, 312 00 Plzeň-Plzeň 4, Czech Republic - E
Plzen
Přeštická 1761/4, Jižní Předměstí, 301 00 Plzeň-Plzeň 3, Czechia
Stops in Brussels
- ARue de France 85, 1060 Saint-Gilles, Belgium
- BBoulevard Simon Bolivar 7, 1030 Schaerbeek, Belgium
- C
Centrale
Rue de Loxum 5, 1000 Bruxelles, Belgium - DPachecolaan 5, 1000 Brussel, Belgium
Compare companies
Frequently asked questions about travelling by bus from Plzeň to Brussels
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Plzeň to Brussels?
The cheapest coach tickets from Plzeň to Brussels start from €54. The average price for this route is around €70. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Plzeň to Brussels?
The average bus journey time from Plzeň to Brussels is 17h 40m, covering a distance of 644 km. The fastest bus can take you there in 10h 30m and is operated by RegioJet.
Which bus companies service the Plzeň to Brussels route?
Several major bus companies operate on this route with 13 buses available per day, including services from FlixBus, RegioJet, BlaBlaCar Bus.
What is the earliest and latest departure time for the bus from Plzeň to Brussels?
The earliest bus departs from Plzeň to Brussels at 01:20. And the latest bus departs at 23:55.
What are the CO₂ emissions for the bus trip from Plzeň to Brussels?
A bus journey from Plzeň to Brussels produces an estimated 16.075575 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Plzeň to Brussels?
According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1073 reviews.
Which company has the best Wi-Fi from Plzeň to Brussels?
Based on Busbud reviews, the bus company RegioJet has the best Wi-Fi rating with a score of 3.8.
Which bus company offers the most punctual service from Plzeň to Brussels?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Plzeň to Brussels?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.4 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Plzeň to Brussels was searched and found on 10 Apr 2026 with a price of €63To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Plzeň to Brussels as early as possible.
What's the cheapest way to go from Plzeň to Brussels?
The Bus is the cheapest travel choice for this destination
