Next train departures

Next departures from Buffalo to Chicago on 17 July
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Train	00:39	Depew Station	10h 33m	10:12	Chicago (Union Station), IL	Cheapest
	Train	00:39	Depew Station	10h 33m	10:12	Chicago (Union Station), IL	Fastest

Next departures from Buffalo to Chicago on 18 July
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Train	00:39	Depew Station	10h 33m	10:12	Chicago (Union Station), IL	Cheapest
	Train	00:39	Depew Station	10h 33m	10:12	Chicago (Union Station), IL	Fastest

Next departures from Buffalo to Chicago on 19 July
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Train	00:39	Depew Station	10h 33m	10:12	Chicago (Union Station), IL	CheapestFastest

Next departures from Buffalo to Chicago on 20 July
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Train	00:39	Depew Station	10h 33m	10:12	Chicago (Union Station), IL	CheapestFastest
	Train	00:39	Depew Station	10h 33m	10:12	Chicago (Union Station), IL	No tags

Next departures from Buffalo to Chicago on 21 July
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	00:39	Depew Station	10h 33m	10:12	Chicago (Union Station), IL	CheapestFastest
Train	00:39	Depew Station	10h 33m	10:12	Chicago (Union Station), IL	No tags
Train	00:39	Depew Station	10h 33m	10:12	Chicago (Union Station), IL	No tags

Next departures from Buffalo to Chicago on 22 July
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	00:39	Depew Station	10h 33m	10:12	Chicago (Union Station), IL	CheapestFastest
Train	00:39	Depew Station	10h 33m	10:12	Chicago (Union Station), IL	No tags
Train	00:39	Depew Station	10h 33m	10:12	Chicago (Union Station), IL	No tags

Next departures from Buffalo to Chicago on 23 July
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	00:39	Depew Station	10h 33m	10:12	Chicago (Union Station), IL	CheapestFastest
Train	00:39	Depew Station	10h 33m	10:12	Chicago (Union Station), IL	No tags
Train	00:39	Depew Station	10h 33m	10:12	Chicago (Union Station), IL	No tags

Last refresh of the prices: Yesterday at 23:08 EDT.

Compare 2 ways to travel from Buffalo to Chicago

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach Chicago. The journey takes about 10 hours 33 minutes and with fares starting at just CLP 61,971, it presents an excellent value for a comfortable ride.

1train per day

10h 33mAverage duration

741 kmDistance

67kgCO₂ emissions

	Average price	Average duration	CO₂ emissions	Actions
Bus	Average priceCLP 54,170 - CLP 152,196	Average duration15h 20m	CO₂ emissions 18kg CO₂e
Train	Average priceCLP 61,971 - CLP 518,151	Average duration10h 33m	CO₂ emissions 67kg CO₂e

Where are the popular train stations and stops in Buffalo, NY and Chicago?

Buffalo, NY

A
Exchange Street Station
75 Exchange St, Buffalo, NY 14203, USA
Visit page

Chicago

A
Union Station
225 S Canal St, Chicago, IL 60606, USA

Train Companies

Amtrak

4.1/55,844 reviews

Staff4.7

Timeliness3.8

Cleanliness4.5

Wi‑Fi3.6

Based on 5844 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the Wi-Fi. Amtrak ticket prices on this trip start at CLP 61,971

US train companies: Amtrak, Amtrak Acela, Brightline

Frequently asked questions about travelling from Buffalo, NY to Chicago by train

Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.

How much does a train ticket cost from Buffalo to Chicago?
The cheapest train tickets from Buffalo to Chicago start from CLP 61,971. The average price for this train route is around CLP 108,084. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the train journey from Buffalo to Chicago?
The average train journey time from Buffalo to Chicago is 10h 33m, covering a distance of 741 km. The fastest train gets you there in 10h 33m and is operated by Amtrak.
Which train operators serve the Buffalo to Chicago route?
Several major train operators run on this route with 1 trains available per day.
What are the earliest and latest departure times for the train from Buffalo to Chicago?
The earliest train from Buffalo to Chicago departs at 00:39. And the latest train departs at 00:39.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

14/07

CLP 181,040

15/07

CLP 181,040

Today

CLP 181,040

17/07

CLP 181,040

18/07

CLP 150,708

19/07

CLP 150,708

20/07

CLP 184,831

21/07

CLP 150,708

The cheapest trip from Buffalo, NY to Chicago was searched and found on 18 Jul 2026 with a price of CLP 150,708

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Buffalo, NY to Chicago as early as possible.

You can expect to pay from CLP 150,708 to CLP 1,368,693 for a train ticket from Buffalo, NY to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at CLP 150,708, which is on 2026-07-18.