Next bus departures

Next departures from Pittsburgh to Chicago on 29 July
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	19:45	Pittsburgh Intermodal Station	11h 25m	06:10	Downtown Greyhound Station	Cheapest
	Bus	19:45	Pittsburgh Intermodal Station	10h 55m	05:40	Chicago 95Th & Dan Ryan	Fastest
	Bus	20:15	Pittsburgh Intermodal Station	13h 10m	08:25	Downtown Greyhound Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	20:15	Pittsburgh Intermodal Station	14h 35m	09:50	Chicago 95Th & Dan Ryan	No tags
	Bus	20:15	Pittsburgh Intermodal Station	12h 45m	08:00	537-517 W. Jackson Blvd	No tags

Next departures from Pittsburgh to Chicago on 30 July
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	08:35	Pittsburgh Intermodal Station	12h 30m	20:05	Downtown Greyhound Station	Cheapest
	Bus	00:55	Pittsburgh Intermodal Station	10h 5m	10:00	Downtown Greyhound Station	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	01:45	Pittsburgh Intermodal Station	12h 40m	13:25	Downtown Greyhound Station	No tags
	Bus	07:10	Pittsburgh Intermodal Station	12h 45m	18:55	Downtown Greyhound Station	No tags
	Bus	08:50	Pittsburgh Intermodal Station	12h 15m	20:05	Downtown Greyhound Station	No tags
	Bus	19:45	Pittsburgh Intermodal Station	11h 25m	06:10	Downtown Greyhound Station	No tags
	Bus	20:15	Pittsburgh Intermodal Station	13h 10m	08:25	Downtown Greyhound Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	01:45	Pittsburgh Intermodal Station	16h 15m	17:00	Chicago 95Th & Dan Ryan	No tags

Next departures from Pittsburgh to Chicago on 31 July
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	08:35	Pittsburgh Intermodal Station	12h 30m	20:05	Downtown Greyhound Station	Cheapest
	Bus	00:55	Pittsburgh Intermodal Station	10h 5m	10:00	Downtown Greyhound Station	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	01:45	Pittsburgh Intermodal Station	12h 40m	13:25	Downtown Greyhound Station	No tags
	Bus	07:10	Pittsburgh Intermodal Station	12h 45m	18:55	Downtown Greyhound Station	No tags
	Bus	08:50	Pittsburgh Intermodal Station	12h 15m	20:05	Downtown Greyhound Station	No tags
	Bus	19:45	Pittsburgh Intermodal Station	11h 25m	06:10	Downtown Greyhound Station	No tags
	Bus	20:15	Pittsburgh Intermodal Station	13h 10m	08:25	Downtown Greyhound Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	01:45	Pittsburgh Intermodal Station	16h 15m	17:00	Chicago 95Th & Dan Ryan	No tags

Next departures from Pittsburgh to Chicago on 1 August
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	08:35	Pittsburgh Intermodal Station	12h 30m	20:05	Downtown Greyhound Station	Cheapest
	Bus	00:55	Pittsburgh Intermodal Station	10h 5m	10:00	Downtown Greyhound Station	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	01:45	Pittsburgh Intermodal Station	12h 40m	13:25	Downtown Greyhound Station	No tags
	Bus	07:10	Pittsburgh Intermodal Station	12h 45m	18:55	Downtown Greyhound Station	No tags
	Bus	08:50	Pittsburgh Intermodal Station	12h 15m	20:05	Downtown Greyhound Station	No tags
	Bus	19:45	Pittsburgh Intermodal Station	11h 25m	06:10	Downtown Greyhound Station	No tags
	Bus	20:15	Pittsburgh Intermodal Station	13h 10m	08:25	Downtown Greyhound Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	01:45	Pittsburgh Intermodal Station	16h 15m	17:00	Chicago 95Th & Dan Ryan	No tags

Next departures from Pittsburgh to Chicago on 2 August
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	19:45	Pittsburgh Intermodal Station	11h 25m	06:10	Downtown Greyhound Station	Cheapest
	Bus	00:55	Pittsburgh Intermodal Station	10h 5m	10:00	Downtown Greyhound Station	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	01:45	Pittsburgh Intermodal Station	12h 40m	13:25	Downtown Greyhound Station	No tags
	Bus	07:10	Pittsburgh Intermodal Station	12h 45m	18:55	Downtown Greyhound Station	No tags
	Bus	08:35	Pittsburgh Intermodal Station	12h 30m	20:05	Downtown Greyhound Station	No tags
	Bus	08:50	Pittsburgh Intermodal Station	12h 15m	20:05	Downtown Greyhound Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	01:45	Pittsburgh Intermodal Station	16h 15m	17:00	Chicago 95Th & Dan Ryan	No tags
	Bus	19:45	Pittsburgh Intermodal Station	10h 55m	05:40	Chicago 95Th & Dan Ryan	No tags

Next departures from Pittsburgh to Chicago on 3 August
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	08:50	Pittsburgh Intermodal Station	12h 15m	20:05	Downtown Greyhound Station	Cheapest
	Bus	00:55	Pittsburgh Intermodal Station	10h 5m	10:00	Downtown Greyhound Station	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	01:45	Pittsburgh Intermodal Station	12h 40m	13:25	Downtown Greyhound Station	No tags
	Bus	07:10	Pittsburgh Intermodal Station	12h 45m	18:55	Downtown Greyhound Station	No tags
	Bus	08:35	Pittsburgh Intermodal Station	12h 30m	20:05	Downtown Greyhound Station	No tags
	Bus	19:45	Pittsburgh Intermodal Station	11h 25m	06:10	Downtown Greyhound Station	No tags
	Bus	20:15	Pittsburgh Intermodal Station	13h 10m	08:25	Downtown Greyhound Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	01:45	Pittsburgh Intermodal Station	16h 15m	17:00	Chicago 95Th & Dan Ryan	No tags

Next departures from Pittsburgh to Chicago on 4 August
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	00:55	Pittsburgh Intermodal Station	10h 5m	10:00	Downtown Greyhound Station	CheapestFastest
Greyhound Lines, Inc. + FlixBus	Bus	01:45	Pittsburgh Intermodal Station	12h 40m	13:25	Downtown Greyhound Station	No tags
	Bus	07:10	Pittsburgh Intermodal Station	12h 45m	18:55	Downtown Greyhound Station	No tags
	Bus	08:35	Pittsburgh Intermodal Station	12h 30m	20:05	Downtown Greyhound Station	No tags
	Bus	08:50	Pittsburgh Intermodal Station	12h 15m	20:05	Downtown Greyhound Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	01:45	Pittsburgh Intermodal Station	16h 15m	17:00	Chicago 95Th & Dan Ryan	No tags
	Bus	20:15	Pittsburgh Intermodal Station	13h 10m	08:25	Downtown Greyhound Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	20:15	Pittsburgh Intermodal Station	14h 35m	09:50	Chicago 95Th & Dan Ryan	No tags

Next departures from Pittsburgh to Chicago on 5 August
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	08:35	Pittsburgh Intermodal Station	12h 30m	20:05	Downtown Greyhound Station	Cheapest
	Bus	00:55	Pittsburgh Intermodal Station	10h 5m	10:00	Downtown Greyhound Station	Fastest
	Bus	01:35	Pittsburgh Intermodal Station	13h 35m	14:10	Downtown Greyhound Station	No tags
	Bus	07:10	Pittsburgh Intermodal Station	12h 45m	18:55	Downtown Greyhound Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	01:45	Pittsburgh Intermodal Station	16h 15m	17:00	Chicago 95Th & Dan Ryan	No tags
	Bus	08:50	Pittsburgh Intermodal Station	12h 15m	20:05	Downtown Greyhound Station	No tags
	Bus	19:45	Pittsburgh Intermodal Station	11h 25m	06:10	Downtown Greyhound Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	20:15	Pittsburgh Intermodal Station	14h 35m	09:50	Chicago 95Th & Dan Ryan	No tags

Last refresh of the prices: Today at 9:27 AM EDT.

Compare 2 ways to travel from Pittsburgh to Chicago

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Chicago. The journey takes about 13 hours and with fares starting at just R 932, it presents an excellent value for a comfortable ride.

17bus per day

13hAverage duration

658 kmDistance

16kgCO₂ emissions

	Average price	Average duration	CO₂ emissions	Actions
Bus	Average priceR 932 - R 4 182	Average duration13h	CO₂ emissions 16kg CO₂e
Train	Average priceR 894 - R 3 332	Average duration9h 46m	CO₂ emissions 60kg CO₂e

Bus stations and stops in Pittsburgh and Chicago

Stops in Pittsburgh

A
Intermodal Station
55 11th St, Pittsburgh, PA 15222, USA
Visit page
B
Sennott Square
201 S Bouquet St, Pittsburgh, PA 15213, USA

Stops in Chicago

A
Downtown Greyhound Station
630 W Harrison St, Chicago, IL 60607, USA
Visit page
B
Chicago O'Hare International Airport
Visit page
C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA
D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA
E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA
F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA

Compare bus companies

Greyhound

3.5/587 588 reviews

Staff3.6

Timeliness2.9

Cleanliness3.4

WiFi2.5

FlixBus

3.5/513 099 reviews

Staff4.2

Timeliness4.0

Cleanliness4.1

WiFi2.7

US bus companies:FlixBus, Greyhound, Futura, Elite, Chihuahuenses, Tufesa, Adirondack Trailways

Frequently asked questions about travelling from Pittsburgh to Chicago by bus

Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.

How much is the bus ticket from Pittsburgh to Chicago?
The cheapest bus tickets from Pittsburgh to Chicago start at R 932. The average price for this route is around R 1 233. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Pittsburgh to Chicago?
The average bus journey time from Pittsburgh to Chicago is 13h, covering a distance of 658 km. The fastest bus gets you there in 9h 55m and is operated by FlixBus.
Which bus companies service the Pittsburgh to Chicago route?
Several major bus companies operate on this route with 17 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from Pittsburgh to Chicago?
The earliest bus departs from Pittsburgh to Chicago at 00:55. And the latest bus departs at 20:15.
What are the CO₂ emissions for the bus trip from Pittsburgh to Chicago?
A bus trip from Pittsburgh to Chicago produces an estimated 16.4469 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Pittsburgh to Chicago?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87588 reviews.
Which bus company has the best Wi-Fi from Pittsburgh to Chicago?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Pittsburgh to Chicago?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Pittsburgh to Chicago?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

27/07

R 1 342

28/07

R 3 664

Today

R 3 096

30/07

R 1 686

31/07

R 1 583

01/08

R 1 204

02/08

R 1 359

03/08

R 1 376

The cheapest trip from Pittsburgh to Chicago was searched and found on 01 Aug 2026 with a price of R 1 204

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pittsburgh to Chicago as early as possible.

You can expect to pay from R 1 204 to R 4 438 for a bus ticket from Pittsburgh to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 204, which is on 2026-08-01.

Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.