Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Prague (Central Bus Station Florenc) | Hotelu Grand | Cheapest | ||||
| Bus | Tomíčkova | Hotelu Grand | Fastest | ||||
Vlak společnosti Gepard Express | Bus | Vaclav Havel Airport Prague | bus station Grand | No tags | ||||
 | Bus | Florenc Bus Terminal | Brno ÚAN Zvonařka | No tags | ||||
 | Bus | Praha [*CZ],,ÚAN Florenc, platform 6, Prague | hotel GRAND, Brno | No tags |
Last refresh of the prices: Today at 9:47 PM CEST.
Compare 2 ways to travel from Prague to Brno
Among the sustainable travel choices, the Bus stands out as a good way to reach Brno. The journey takes about 2 hours 35 minutes and with fares starting at just THB 342, it presents an excellent value for a comfortable ride.
Where are the popular stops in Prague and Brno?
Stops in Prague
- AAviatická, 161 08, Praha 6, Czechia
- BTomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
- CChlumecká, 198 00 Praha 20, Czech Republic
- DKřižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
- E
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic - F300/8 Wilsonova, 110 00 Praha, Czechia
Stops in Brno
- ABenešova 603/2, Brno-město, 602 00 Brno-Brno-střed, Czech Republic
- BBrno Bus Station, ÚAN Zvonařka, 602 00 Brno-střed, Czechia
- CNádražní 418/1, Brno-město, 602 00 Brno-Brno-střed, Czechia
- DZvonařka 411, Trnitá, 602 00 Brno-Brno-střed, Czech Republic
- E
Ústřední hřbitov
Vídeňská 306/94, Štýřice, 639 00 Brno-Brno-střed, Czechia - F
Vídeňská 98
Vídeňská 98, 619 00 Brno-jih, Czechia
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Frequently asked questions about travelling from Prague to Brno by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Prague to Brno?
The cheapest bus tickets from Prague to Brno start at THB 342. The average price for this route is around THB 446. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Prague to Brno?
The average bus journey time from Prague to Brno is 2h 35m, covering a distance of 188 km. The fastest bus gets you there in 2h and is operated by Maksymiuk FOP.
Which bus companies service the Prague to Brno route?
Several major bus companies operate on this route with 66 buses available per day, including services from FlixBus, RegioJet, IC Bus, Slovak Lines, A-Express, Musil Tour, Maksymiuk FOP, AMI-TOUR, Avtokombinat-1 OOO, Gepard Express, Monobus.
What is the earliest and latest departure time for the bus from Prague to Brno?
The earliest bus departs from Prague to Brno at 01:45. And the latest bus departs at 23:25.
What are the CO₂ emissions for the bus trip from Prague to Brno?
A bus trip from Prague to Brno produces an estimated 4.691299999999999 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Prague to Brno?
According to Busbud customers, the highest-rated bus company on this route is IC Bus, with an average rating of 4.5 out of 5 stars based on 20 reviews.
Which bus company has the best Wi-Fi from Prague to Brno?
Based on reviews on Busbud, the bus company Slovak Lines has the best Wi-Fi rating with a score of 4.2.
Which bus company offers the most punctual service from Prague to Brno?
According to Busbud traveller reviews, the most punctual bus company on this route is IC Bus, with a punctuality rating of 5.0 out of 5 stars.
Which bus company has the cleanest buses from Prague to Brno?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is IC Bus, with a cleanliness rating of 5.0 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Prague to Brno was searched and found on 01 Jun 2026 with a price of THB 219To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Brno as early as possible.
You can expect to pay from THB 219 to THB 5 589 for a bus ticket from Prague to Brno based on the last 2 days. You can expect to find the cheapest price for the trip at THB 219, which is on 2026-06-01.
Usually AMI-TOUR will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Prague to Brno?
The Bus is the cheapest travel choice for this destination
