Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Ayer MA | Knoxville Bus Station | No tags |
Get from Ayer to Knoxville
The journey takes about 1 day, 5 hours 20 minutes and with fares starting at just ¥17,687, it presents an excellent value for a comfortable ride.
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Ayer to Knoxville, TN by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Ayer to Knoxville?
The cheapest bus tickets from Ayer to Knoxville start from ¥17,687. The average price for this route is around ¥17,687. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Ayer to Knoxville?
The average bus trip duration from Ayer to Knoxville is 1d 5h, covering a distance of 796 miles (1283 km). The quickest bus can get you there in 1d 5h and is operated by Greyhound.
Which bus companies service the Ayer to Knoxville route?
Several major bus companies operate on this route with 1 buses available per day.
What is the earliest and latest departure time for the bus from Ayer to Knoxville?
The earliest bus departs from Ayer to Knoxville at 12:40pm. And the latest bus departs at 12:40pm.
What are the CO₂ emissions for the bus trip from Ayer to Knoxville?
A bus trip from Ayer to Knoxville generates an estimated 32.07005 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Ayer to Knoxville, TN was searched and found on May 12, 2026 with a price of ¥16,536To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Ayer to Knoxville, TN, as early as possible.
You can expect to pay from ¥16,536 to ¥16,536 for a bus ticket from Ayer to Knoxville, TN based on the last 2 days. You can expect to find the cheapest price for the trip at ¥16,536 which is on 2026-05-12.
