Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Boston (South Station) | Frederick | No tags | ||||
Greyhound + FlixBus | Bus | 151 Steel Pl, Cambridge | Frederick | No tags | ||||
Greyhound + FlixBus | Bus | 151 Steel Pl, Cambridge | Frederick | No tags | ||||
FlixBus + Greyhound | Bus | 151 Steel Pl, Cambridge | Frederick | No tags | ||||
| Bus | Boston (South Station) | Frederick | No tags |
Get from Boston to Frederick
The journey takes about 17 hours 55 minutes and with fares starting at just $60, it presents an excellent value for a comfortable ride.
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Boston, MA, US to Frederick by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Boston to Frederick?
The cheapest bus tickets from Boston to Frederick start from $60. The average price for this route is around $75. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Boston to Frederick?
The average bus trip duration from Boston to Frederick is 17h 55m, covering a distance of 388 miles (626 km). The quickest bus can get you there in 12h 5m and is operated by Greyhound.
Which bus companies service the Boston to Frederick route?
Several major bus companies operate on this route with 5 buses available per day.
What is the earliest and latest departure time for the bus from Boston to Frederick?
The earliest bus departs from Boston to Frederick at 1:30am. And the latest bus departs at 9:50pm.
What are the CO₂ emissions for the bus trip from Boston to Frederick?
A bus trip from Boston to Frederick generates an estimated 15.640075 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Boston, MA, US to Frederick was searched and found on Apr 15, 2026 with a price of $61To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Boston, MA, US to Frederick, as early as possible.
You can expect to pay from $61 to $80 for a bus ticket from Boston, MA, US to Frederick based on the last 2 days. You can expect to find the cheapest price for the trip at $61 which is on 2026-04-15.
