Next bus departures

Next departures for Cincinnati to St. Louis on September 28
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus Wifi Toilet Power outlets	2:10pm	Cincinnati (Downtown)	10h 5m	11:15pm	Gateway Station	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus Wifi Toilet Power outlets	3:00pm	Cincinnati (University of Cincinnati)	9h 15m	11:15pm	Gateway Station	Fastest
	Bus Wifi Toilet Power outlets	10:05am	Cincinnati Bus Station	14h 10m	11:15pm	Gateway Station	No tags

Next departures for Cincinnati to St. Louis on September 30
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus Wifi Toilet Power outlets	10:05am	Cincinnati Bus Station	14h 10m	11:15pm	Gateway Station	Cheapest
Bus Wifi Toilet Power outlets	4:40am	Cincinnati Bus Station	11h 30m	3:10pm	Gateway Station	Fastest
Bus Wifi Toilet Power outlets	10:25am	Cincinnati (Downtown)	13h 50m	11:15pm	Gateway Station	No tags

Next departures for Cincinnati to St. Louis on October 1
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus Wifi Toilet Power outlets	10:05am	Cincinnati Bus Station	14h 10m	11:15pm	Gateway Station	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus Wifi Toilet Power outlets	3:00pm	Cincinnati (University of Cincinnati)	9h 15m	11:15pm	Gateway Station	Fastest
	Bus Wifi Toilet Power outlets	4:40am	Cincinnati Bus Station	11h 30m	3:10pm	Gateway Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus Wifi Toilet Power outlets	2:35pm	Cincinnati (Downtown)	9h 40m	11:15pm	Gateway Station	No tags

Last refresh of the prices: Last Saturday at 11:21 AM EDT.

Compare 2 ways to go from Cincinnati to St. Louis

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach St. Louis. The journey takes about 10 hours 5 minutes and with fares starting at just COP 189,425, it presents an excellent value for a comfortable ride.

4bus per day

10h 5mAverage Duration

310 milesDistance

12kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average PriceCOP 189,425 - COP 636,053	Average Duration10h 5m	CO₂ emissions 12kg CO₂e
Train	Average PriceCOP 338,381 - COP 729,494	Average Duration18h 4m	CO₂ emissions 45kg CO₂e

Bus stations and stops in Cincinnati and St. Louis

Stops in Cincinnati

A
Greyhound Station
1005 Gilbert Ave, Cincinnati, OH 45202
Visit page
B
Northland Blvd
290-322 Northland Blvd, Springdale, OH 45246, USA

Stops in St. Louis

A
Gateway Station
430 S 15th St, St Louis, MO 63103
Visit page

Compare bus companies

Greyhound

3.5/588,182 reviews

Staff3.6

Timeliness3.0

Cleanliness3.4

Wifi2.5

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/515,938 reviews

Staff4.2

Timeliness4.0

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies:FlixBus, Greyhound, Futura, Tufesa, Chihuahuenses, Adirondack Trailways, Valley Transit

Frequently asked questions about traveling from Cincinnati to St. Louis by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Cincinnati to St. Louis?
The cheapest bus tickets from Cincinnati to St. Louis start from COP 189,425. The average price for this route is around COP 253,013. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Cincinnati to St. Louis?
The average bus trip duration from Cincinnati to St. Louis is 10h 5m, covering a distance of 310 miles (499 km). The quickest bus can get you there in 11h 30m and is operated by Greyhound.
Which bus companies service the Cincinnati to St. Louis route?
Several major bus companies operate on this route with 4 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from Cincinnati to St. Louis?
The earliest bus departs from Cincinnati to St. Louis at 12:55am. And the latest bus departs at 3:00pm.
What are the CO₂ emissions for the bus trip from Cincinnati to St. Louis?
A bus trip from Cincinnati to St. Louis generates an estimated 12.460775 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Cincinnati to St. Louis?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 88149 reviews.
Which bus company has the best Wi-Fi from Cincinnati to St. Louis?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Cincinnati to St. Louis?
According to Busbud traveler reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Cincinnati to St. Louis?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

09/26

COP 264,418

09/27

COP 358,890

Today

COP 261,017

09/29

No data

09/30

COP 206,018

10/01

COP 193,994

10/02

COP 192,276

10/03

COP 185,406

The cheapest trip from Cincinnati to St. Louis was searched and found on Oct 3, 2026 with a price of COP 185,406

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Cincinnati to St. Louis, as early as possible.

You can expect to pay from COP 185,406 to COP 377,819 for a bus ticket from Cincinnati to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at COP 185,406 which is on 2026-10-03.