Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Price and booking link |
|---|---|---|---|---|---|---|---|
Greyhound + FlixBus | Bus | Lewiston (Bates College) | Florence, SC | ||||
FlixBus + Greyhound | Bus | KM Transit Bus Stop Lewiston | Florence, SC | ||||
FlixBus + Greyhound | Bus | Lewiston (Bates College) | Bus station | ||||
FlixBus + Greyhound | Bus | Lewiston (Bates College) | Florence, SC | ||||
FlixBus + Greyhound | Bus | KM Transit Bus Stop Lewiston | Bus station |
Get from Lewiston to Florence
The journey takes about 23 hours 5 minutes and with fares starting at just COP 460,048, it presents an excellent value for a comfortable ride.
Where are the popular stops in Lewiston and Florence?
Stops in Florence
- A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA - B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Lewiston, ME to Florence, SC, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Lewiston to Florence?
The cheapest bus tickets from Lewiston to Florence start from COP 460,048. The average price for this route is around COP 593,471. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Lewiston to Florence?
The average bus trip duration from Lewiston to Florence is 23h 5m, covering a distance of 852 miles (1374 km). The quickest bus can get you there in 23h and is operated by Greyhound.
Which bus companies service the Lewiston to Florence route?
Several major bus companies operate on this route with 3 buses available per day.
What is the earliest and latest departure time for the bus from Lewiston to Florence?
The earliest bus departs from Lewiston to Florence at 12:40pm. And the latest bus departs at 12:45pm.
What are the CO₂ emissions for the bus trip from Lewiston to Florence?
A bus trip from Lewiston to Florence generates an estimated 34.34705 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Lewiston, ME to Florence, SC, US was searched and found on Jun 7, 2026 with a price of COP 439,034To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lewiston, ME to Florence, SC, US, as early as possible.
You can expect to pay from COP 439,034 to COP 516,864 for a bus ticket from Lewiston, ME to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at COP 516,864 which is on 2026-06-10.
