Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Minneapolis | La Crosse (U of WI) | Cheapest | ||||
| Bus | Minneapolis (U of MN - Huron Blvd) | 314 Jay St., La Crosse | Fastest | ||||
| Bus | Minneapolis (U of MN - Huron Blvd) | La Crosse (U of WI) | No tags | ||||
| Bus | Minneapolis | 314 Jay St., La Crosse | No tags |
Last refresh of the prices: Yesterday at 1:49 PM CDT.
Get from Minneapolis to La Crosse
The journey takes about 4 hours 5 minutes and with fares starting at just CLP 27,450, it presents an excellent value for a comfortable ride.
Compare bus companies
Founded in 1919, Jefferson Lines provides bus services across the Midwest in the US. Their buses have WiFi, USB plugs, bathrooms, reclining seats, reading lights and GPS tracking. Tickets are non-refundable, but you can change the date by paying a fee. Known for their affordable prices and convenient schedules, if you're looking to travel in the Midwest, Jefferson Lines is the way to go.
Jefferson Lines Minneapolis La Crosse recent customer reviews
First time on bus. Both people in Minneapoles terminal very helpful as I had questions. Driver and assistant also nice.
David S.
Frequently asked questions about traveling from Minneapolis to La Crosse, WI by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Minneapolis to La Crosse?
The cheapest bus tickets from Minneapolis to La Crosse start from CLP 27,450. The average price for this route is around CLP 27,450. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Minneapolis to La Crosse?
The average bus trip duration from Minneapolis to La Crosse is 4h 5m, covering a distance of 126 miles (203 km). The quickest bus can get you there in 3h 10m and is operated by Jefferson Lines.
Which bus companies service the Minneapolis to La Crosse route?
Several major bus companies operate on this route with 7 buses available per day.
What is the earliest and latest departure time for the bus from Minneapolis to La Crosse?
The earliest bus departs from Minneapolis to La Crosse at 9:30am. And the latest bus departs at 3:15pm.
What are the CO₂ emissions for the bus trip from Minneapolis to La Crosse?
A bus trip from Minneapolis to La Crosse generates an estimated 5.058350000000001 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Minneapolis to La Crosse, WI was searched and found on May 10, 2026 with a price of CLP 26,535To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Minneapolis to La Crosse, WI, as early as possible.
Top traveled bus routes
People from around the world trust Busbud
Popular bus departures from Minneapolis
- Find bus tickets from Minneapolis to Duluth
- Minneapolis to Fargo bus times and fares
- How to travel from Minneapolis to Indianapolis
- Find bus tickets from Minneapolis to Madison
- Minneapolis to Green Bay bus times and fares
- How to travel from Minneapolis to Chicago
- Find bus tickets from Minneapolis to Milwaukee