Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus
| Orlando Bus Station | Key West Bus Station | Cheapest | ||||
FlixBus + Greyhound Lines, Inc. | Bus
| The Florida Mall | Key West Bus Station | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus
| Orlando Bus Station | Key West Bus Station | No tags | ||||
 | Bus
| Orlando Bus Station | Key West Bus Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus
| The Florida Mall | Key West Bus Station | No tags |
Last refresh of the prices: Yesterday at 8:46 PM EDT.
Get from Orlando to Key West
The journey takes about 10 hours 25 minutes and with fares starting at just CZK 1,134, it presents an excellent value for a comfortable ride.
Bus stations and stops in Orlando and Key West
Stops in Orlando
- A
Orlando Bus Station
555 N John Young Pkwy, Orlando, FL 32805 - B
Orlando RedCoach Station
RedCoach Station, 1777 McCoy Road, Orlando, FL 32809 - C
Jet Set Express Terminal
Jet Set Express Terminal, 3718 LB Mcleod Rd., 32805 Orlando, FL,, United States - D
Disney World
Disney's All-Star Sports Resort, 1701 West Buena Vista Dr., Orlando, FL 32830 - E
International Dr SuperTours Terminal
5419 International Dr, Orlando, FL 32819, USA - F
Seaworld Hotels
10100 International Drive , Orlando, 32821
Stops in Key West
- A
EYW Airport
3535 Florida A1A, Key West, FL 33040, USA - B
Caroline St
908 Caroline St, Key West, FL 33040, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Orlando Key West recent customer reviews
Overall very unhappy with this trip. Bus was 2 hours late, staff on the bus, driver was courteous but the other “helper” was rude and no help at all. I asked him for options or ideas so I could make it down to Key West on time for an appointment and he couldn’t be bothered, even though he was just sitting in the front doing nothing. Because the bus was 2 hours late getting to Miami, I missed my bus to Key West. The staff at Miami was extremely slow and I found a shuttle in the meantime to take me there instead so I could make my appointment.
Derek S.
Good journey
Denise B.
Great bus driver all the way to key West
Donald C.
Frequently asked questions about traveling from Orlando to Key West by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Orlando to Key West?
The cheapest bus tickets from Orlando to Key West start from CZK 1,134. The average price for this route is around CZK 1,546. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Orlando to Key West?
The average bus trip duration from Orlando to Key West is 10h 25m, covering a distance of 274 miles (441 km). The quickest bus can get you there in 10h 25m and is operated by Greyhound.
Which bus companies service the Orlando to Key West route?
Several major bus companies operate on this route with 5 buses available per day.
What is the earliest and latest departure time for the bus from Orlando to Key West?
The earliest bus departs from Orlando to Key West at 12:45am. And the latest bus departs at 11:05pm.
What are the CO₂ emissions for the bus trip from Orlando to Key West?
A bus trip from Orlando to Key West generates an estimated 11.02075 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Orlando to Key West was searched and found on Sep 22, 2026 with a price of CZK 1,010To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to Key West, as early as possible.
You can expect to pay from CZK 1,010 to CZK 1,651 for a bus ticket from Orlando to Key West based on the last 2 days. You can expect to find the cheapest price for the trip at CZK 1,010 which is on 2026-09-22.
