Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Santander (Estacion de Autobuses) | Lisbon (Oriente) | CheapestFastest | ||||
| Bus | Santander (Estacion de Autobuses) | Lisbon (Oriente) | No tags | ||||
| Bus | Santander (Estacion de Autobuses) | Aeroporto Lisboa | No tags |
Last refresh of the prices: Yesterday at 9:54 PM CEST.
Get from Santander to Lisbon
The journey takes about 15 hours 45 minutes and with fares starting at just CLP 71,010, it presents an excellent value for a comfortable ride.
Bus stations and stops in Santander and Lisbon
Stops in Santander
- A
Calle Navas de Tolosa, 2
Calle Navas de Tolosa, 2, 39002 Santander, Cantabria, Spain - C
Av. de los Castros 43A
Av. de los Castros 43A, 39005 Santander, Cantabria, Spain - D
Calle Camarreal-Ojaiz
Calle Camarreal-Ojaiz, 52, 39011 Santander, Cantabria, Spain - E
Av. de Pontejos
Av. de Pontejos, 33A, 39005 Santander, Cantabria, Spain - F
Estación Marítima
39002 Santander, Cantabria, Spain
Stops in Lisbon
- A
Oriente
Estação do Oriente, Av. Dom João II, 1990, Portugal - B
Lisbon Sete Rios
R. Prof. Lima Basto 133, 1500-423 Lisboa, Portugal - D
Plaça Marquês de Pombal
Praça Marquês de Pombal 8, 1250-160 Lisboa, Portugal - E
Monsanto
IC15, 1400 Lisboa, Portugal - F
Largo das Olarias 60
Largo das Olarias 60, 1100-376 Lisboa, Portugal
Compare bus companies
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Santander to Lisbon by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Santander to Lisbon?
The cheapest bus tickets from Santander to Lisbon start from CLP 71,010. The average price for this route is around CLP 103,753. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Santander to Lisbon?
The average bus trip duration from Santander to Lisbon is 15h 45m, covering a distance of 425 miles (685 km). The quickest bus can get you there in 14h 35m and is operated by FlixBus.
Which bus companies service the Santander to Lisbon route?
Several major bus companies operate on this route with 3 buses available per day.
What is the earliest and latest departure time for the bus from Santander to Lisbon?
The earliest bus departs from Santander to Lisbon at 9:25am. And the latest bus departs at 6:55pm.
What are the CO₂ emissions for the bus trip from Santander to Lisbon?
A bus trip from Santander to Lisbon generates an estimated 17.116425 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santander to Lisbon was searched and found on Aug 4, 2026 with a price of CLP 73,316To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santander to Lisbon, as early as possible.
You can expect to pay from CLP 73,316 to CLP 113,225 for a bus ticket from Santander to Lisbon based on the last 2 days. You can expect to find the cheapest price for the trip at CLP 76,382 which is on 2026-08-08.
