Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Terminal Interbus | Aeroporto Ciampino Airport (CIA) | No tags | ||||
| Bus | Terminal Interbus | Rome Tiburtina Bus Station | No tags | ||||
| Bus | Terminal Interbus | Rome Anagnina | No tags | ||||
| Bus | Terminal Interbus | Rome Fiumicino Airport | No tags | ||||
| Bus | Terminal Interbus | Aeroporto Ciampino Airport (CIA) | No tags |
Compare 2 ways to go from Syracuse to Rome
Among the sustainable travel choices, the Train stands out as a good way to reach Rome. The journey takes about 10 hours 58 minutes and with fares starting at just $67, it presents an excellent value for a comfortable ride.
Where are the popular stops in Syracuse and Rome?
Stops in Syracuse
- A
S. Teresa Longarini
Via Elorina, 129, 96100 Siracusa SR, Italy - BViale Paolo Orsi, 20, 96100 Siracusa SR, Italy
- C
Siracusa
Piazzale della Stazione Centrale, 21, 96100 Siracusa SR, Italy - D
Siracusa - Terminal Bus (Stazione FS)
Viale Teocrito, 68-74, 96100 Siracusa SR, Italy
Stops in Rome
- APiazza dei Cinquecento 1, 00185 Roma RM, Italy
- BLargo Guido Mazzoni, 3, 00162 Roma, Italy
- C
Rome Fiumicino Airport (FCO), Train station
Fiumicino Aeroporto, 00054 Fiumicino RM, Italy - DRoma S.Pietro, 00165 Roma RM, Italy
- ERoma Trastevere Railway Station, 00152 Roma RM, Italy
- FCesano Di Roma, 00123 Roma RM, Italy
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Frequently asked questions about traveling from Syracuse to Rome by bus or train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is a ticket from Syracuse to Rome?
The cheapest tickets from Syracuse to Rome start from $47. The average price for this route is around $87. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the ride from Syracuse to Rome?
The average trip duration from Syracuse to Rome is 14h 6m, covering a distance of 365 miles (588 km). The quickest vehicle can get you there in 10h 51m and is operated by Trenitalia.
Which companies service the Syracuse to Rome route?
Several major companies operate on this route with 2 trips available per day, including services from FlixBus, Trenitalia.
What is the earliest and latest departure time from Syracuse to Rome?
The earliest trip departs from Syracuse to Rome at 7:15am. And the latest trip departs at 9:50pm.
What are the CO₂ emissions for the trip from Syracuse to Rome?
A trip from Syracuse to Rome generates an estimated 14.67775 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best company from Syracuse to Rome?
According to Busbud customers, the highest-rated company on this route is Trenitalia, with an average rating of 3.9 out of 5 stars based on 58 reviews.
Which company has the best Wi-Fi from Syracuse to Rome?
Based on reviews on Busbud, the company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which company has the most timely service from Syracuse to Rome?
According to Busbud traveler reviews, the most timely company on this route is Trenitalia, with a punctuality rating of 4.6 out of 5 stars.
Which company has the cleanest vehicles from Syracuse to Rome?
According to Busbud traveler reviews, the company with the cleanest vehicles on this route is Trenitalia, with a cleanliness rating of 4.7 out of 5 stars.
Find cheapest prices for buses and trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Syracuse to Rome was searched and found on Apr 15, 2026 with a price of $52To save money and be sure you have the best seat, it's a good idea to buy your bus and train tickets from Syracuse to Rome, as early as possible.
You can expect to pay from $52 to $135 for a bus or train ticket from Syracuse to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at $52 which is on 2026-04-15.
Usually Trenitalia will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Syracuse to Rome?
The Bus is the cheapest travel choice for this destination
