How much is the bus ticket from Wilmington to Florence?

The cheapest bus tickets from Wilmington to Florence start from $65. The average price for this route is around $132. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Wilmington to Florence?

The average bus trip duration from Wilmington to Florence is 18h 25m, covering a distance of 439 miles (708 km). The quickest bus can get you there in 12h 55m and is operated by FlixBus .

Which bus companies service the Wilmington to Florence route?

Several major bus companies operate on this route with 6 buses available per day.

What is the earliest and latest departure time for the bus from Wilmington to Florence?

The earliest bus departs from Wilmington to Florence at 11:20am. And the latest bus departs at 9:25pm.

What are the CO₂ emissions for the bus trip from Wilmington to Florence?

A bus trip from Wilmington to Florence generates an estimated 17.6795 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

Bus Wilmington to Florence from $65 | Refundable Tickets

Previously seen trips

Next departures for Wilmington to Florence on April 11
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound	Bus	9:25pm	Wilmington Bus Station	1d 2h	11:59pm	Florence, SC	No tags
Greyhound + FlixBus	Bus	1:50pm	Wilmington Bus Station	15h 45m	5:35am	Florence, SC	No tags
Greyhound + FlixBus	Bus	1:50pm	Wilmington Bus Station	15h 40m	5:30am	Florence, SC	No tags
Greyhound + FlixBus	Bus	9:25pm	Wilmington Bus Station	15h 20m	12:45pm	Bus station	No tags
Greyhound + FlixBus	Bus	1:50pm	Wilmington Bus Station	15h 45m	5:35am	Florence, SC	No tags

Compare 2 ways to go from Wilmington to Florence

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach Florence. The journey takes about 11 hours 4 minutes and with fares starting at just $96, it presents an excellent value for a comfortable ride.

3train per day

11h 4mAverage Duration

447 milesDistance

66kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$65 - $231	Average Duration18h 25m	CO₂ emissions 18kg CO₂e
Train	Average Price$96 - $472	Average Duration11h 4m	CO₂ emissions 66kg CO₂e

Where are the popular stops in Wilmington and Florence?

Stops in Wilmington

A
Wilmington Bus Station
Wilmington Bus Station, 101 N French St, Wilmington, DE 19801, USA
Visit page
B
Wilmington Station
100 French St, Wilmington, DE 19801, USA
Visit page
C
Wilmington Bus Stop
101 N French , Wilmington, DE 19801

Stops in Florence

A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA
Visit page
B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA

Compare bus companies

FlixBus

3.5/512,452 reviews

Staff4.2

Timeliness4.0

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies:FlixBus, Greyhound, BlaBlaCar Bus, Intercape, ALSA, Trenitalia, Big Sky

Frequently asked questions about traveling from Wilmington, DE to Florence, SC, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Wilmington to Florence?
The cheapest bus tickets from Wilmington to Florence start from $65. The average price for this route is around $132. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Wilmington to Florence?
The average bus trip duration from Wilmington to Florence is 18h 25m, covering a distance of 439 miles (708 km). The quickest bus can get you there in 12h 55m and is operated by FlixBus.
Which bus companies service the Wilmington to Florence route?
Several major bus companies operate on this route with 6 buses available per day.
What is the earliest and latest departure time for the bus from Wilmington to Florence?
The earliest bus departs from Wilmington to Florence at 11:20am. And the latest bus departs at 9:25pm.
What are the CO₂ emissions for the bus trip from Wilmington to Florence?
A bus trip from Wilmington to Florence generates an estimated 17.6795 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

04/09

$105

04/10

$83

Today

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04/12

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04/13

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04/14

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04/15

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04/16

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The cheapest trip from Wilmington, DE to Florence, SC, US was searched and found on Apr 10, 2026 with a price of $83

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Wilmington, DE to Florence, SC, US, as early as possible.