Bus and Train from Pisa to Rome: Tickets & Schedules

Next available departures

Next departures for Pisa to Rome on September 14
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Flixbus
  • Wifi
  • Toilet
  • Power outlets
Parcheggio Via Pietransantina
Rome Tiburtina Bus StationCheapest
Trenitalia FRECCIABIANCA
  • Wifi
  • Toilet
  • Power outlets
Piazza della Stazione, 10
TerminiFastest
MarinoBus
  • Toilet
Fermata dell'autobus Pisa
Rome Tiburtina Bus StationNo tags
Trenitalia Regionale Veloce
  • Wifi
  • Toilet
  • Power outlets
Piazza della Stazione, 10
TerminiNo tags
Flixbus
  • Wifi
  • Toilet
  • Power outlets
park Aurelia
Rome Tiburtina Bus StationNo tags
Trenitalia FRECCIABIANCA
  • Wifi
  • Toilet
  • Power outlets
Piazza della Stazione, 10
TerminiNo tags
Flixbus
  • Wifi
  • Toilet
  • Power outlets
Parcheggio Via Pietransantina
Rome Tiburtina Bus StationNo tags
Trenitalia FRECCIABIANCA
  • Wifi
  • Toilet
  • Power outlets
Piazza della Stazione, 10
TerminiNo tags

Last refresh of the prices: Today at 9:58 AM CEST.

Compare 2 ways to go from Pisa to Rome

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach Rome. The journey takes about 3 hours 45 minutes and with fares starting at just COP 72,729, it presents an excellent value for a comfortable ride.

12train per day
3h 45mAverage Duration
165 milesDistance
6kgCO₂ emissions
Bus
Average PriceCOP 52,917 - COP 575,876Average Duration5h 50m
7kg CO₂e
Train
Average PriceCOP 72,729 - COP 641,736Average Duration3h 45m
6kg CO₂e

Frequently asked questions about traveling from Pisa to Rome by bus or train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is a ticket from Pisa to Rome?

    The cheapest tickets from Pisa to Rome start from COP 52,917. The average price for this route is around COP 102,795. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the ride from Pisa to Rome?

    The average trip duration from Pisa to Rome is 4h 47m, covering a distance of 166 miles (267 km). The quickest vehicle can get you there in 2h 9m and is operated by Trenitalia.

  3. Which companies service the Pisa to Rome route?

    Several major companies operate on this route with 12 trips available per day, including services from FlixBus, MarinoBus, BusItalia, Itabus, Trenitalia.

  4. What is the earliest and latest departure time from Pisa to Rome?

    The earliest trip departs from Pisa to Rome at 12:25am. And the latest trip departs at 11:30pm.

  5. What are the CO₂ emissions for the trip from Pisa to Rome?

    A trip from Pisa to Rome generates an estimated 6.6649625 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

  6. What is the best company from Pisa to Rome?

    According to Busbud customers, the highest-rated company on this route is MarinoBus, with an average rating of 4.1 out of 5 stars based on 976 reviews.

  7. Which company has the best Wi-Fi from Pisa to Rome?

    Based on reviews on Busbud, the company BusItalia has the best Wi-Fi rating with a score of 3.9.

  8. Which company has the most timely service from Pisa to Rome?

    According to Busbud traveler reviews, the most timely company on this route is Trenitalia, with a punctuality rating of 4.4 out of 5 stars.

  9. Which company has the cleanest vehicles from Pisa to Rome?

    According to Busbud traveler reviews, the company with the cleanest vehicles on this route is Trenitalia, with a cleanliness rating of 4.8 out of 5 stars.

Find cheapest prices for buses and trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/11
COP 102,985
09/12
COP 75,197
Today
COP 92,161
09/14
COP 45,131
09/15
COP 56,366
09/16
COP 56,366
09/17
COP 46,998
09/18
COP 56,430
busbud logoThe cheapest trip from Pisa to Rome was searched and found on Sep 14, 2026 with a price of COP 45,131

To save money and be sure you have the best seat, it's a good idea to buy your bus and train tickets from Pisa to Rome, as early as possible.

You can expect to pay from COP 45,131 to COP 530,587 for a bus or train ticket from Pisa to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at COP 45,131 which is on 2026-09-14.

Usually Trenitalia will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

What's the cheapest way to go from Pisa to Rome?

busbud logoThe Bus is the cheapest travel choice for this destination

People from around the world trust Busbud

‌