Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Price and booking link |
|---|---|---|---|---|---|---|---|
 | Bus | Rome Tiburtina Bus Station | Terminal Interbus | ||||
| Bus | Rome Tiburtina Bus Station | Terminal Interbus | ||||
| Bus | Rome Tiburtina Bus Station | Terminal Interbus | ||||
| Bus | Rome Anagnina | Terminal Interbus | ||||
| Bus | Rome Tiburtina Bus Station | Terminal Interbus |
Compare 2 ways to travel from Rome to Syracuse
Among the sustainable travel choices, the Train stands out as a good way to reach Syracuse. The journey takes about 11 hours 11 minutes and with fares starting at just R 1 291, it presents an excellent value for a comfortable ride.
Bus stations and stops in Rome and Syracuse
Stops in Rome
- A
Termini
Piazza dei Cinquecento 1, 00185 Roma RM, Italy - B
Rome Tiburtina Bus Station
Largo Guido Mazzoni, 3, 00162 Roma, Italy - C
Rome Fiumicino Airport (FCO), Train station
Fiumicino Aeroporto, 00054 Fiumicino RM, Italy - D
Roma S. Pietro
Roma S.Pietro, 00165 Roma RM, Italy - F
Roma Trastevere
Roma Trastevere Railway Station, 00152 Roma RM, Italy
Stops in Syracuse
- A
S. Teresa Longarini
Via Elorina, 129, 96100 Siracusa SR, Italy - B
Fermata dell'autobus Siracusa
Viale Paolo Orsi, 20, 96100 Siracusa SR, Italy - C
Siracusa
Piazzale della Stazione Centrale, 21, 96100 Siracusa SR, Italy - D
Siracusa - Terminal Bus (Stazione FS)
Viale Teocrito, 68-74, 96100 Siracusa SR, Italy
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Frequently asked questions about travelling from Rome to Syracuse by bus or train
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is a ticket from Rome to Syracuse?
The cheapest tickets from Rome to Syracuse start at R 539. The average price for this route is around R 1 283. Busbud recommends booking your tickets in advance for a better chance of getting the lowest possible price.
How long is the journey from Rome to Syracuse?
The average trip duration from Rome to Syracuse is 16h 35m, covering a distance of 586 km. The quickest vehicle can get you there in 11h 11m and is operated by Trenitalia.
Which companies operate the Rome to Syracuse route?
Several major companies operate on this route with 1 trips available per day, including services from FlixBus, Trenitalia.
What are the earliest and latest departure times from Rome to Syracuse?
The earliest trip from Rome to Syracuse departs at 02:45. The latest trip departs at 23:55.
What are the CO₂ emissions for the journey from Rome to Syracuse?
A trip from Rome to Syracuse generates an estimated 14.634649999999999 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Which is the best company from Rome to Syracuse?
According to Busbud customers, the highest-rated company on this route is Trenitalia, with an average rating of 3.9 out of 5 stars based on 69 reviews.
Which company has the best Wi-Fi from Rome to Syracuse?
Based on reviews on Busbud, the company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which company has the most punctual service from Rome to Syracuse?
According to Busbud traveller reviews, the most punctual company on this route is Trenitalia, with a punctuality rating of 4.4 out of 5 stars.
Which company has the cleanest vehicles from Rome to Syracuse?
According to Busbud traveller reviews, the company with the cleanest vehicles on this route is Trenitalia, with a cleanliness rating of 4.7 out of 5 stars.
Find the cheapest prices for buses and trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Rome to Syracuse was searched and found on 08 Sept 2026 with a price of R 544To save money and make sure you get the best seat, it's a good idea to buy your bus and train tickets from Rome to Syracuse, as early as possible.
You can expect to pay between R 544 and R 1 838 for a bus or train ticket from Rome to Syracuse based on the past 2 days. You can expect to find the lowest price for the trip at R 544 which is on 2026-09-08.
What's the cheapest way to go from Rome to Syracuse?
The Bus is the cheapest travel choice for this destination
