Next available departures

Next departures for Isernia to Rome on August 21
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
8:50am	Isernia	2h 30m	11:20am	Termini	Cheapest
11:35am	Isernia	2h 25m	2:00pm	Rome Tiburtina Bus Station	Fastest
3:15pm	Isernia	2h 30m	5:45pm	Termini	No tags
11:35am	Isernia	9h 40m	9:15pm	Rome Fiumicino Airport	No tags
6:15pm	Isernia	6h 45m	1:00am	Rome Fiumicino Airport	No tags

Next departures for Isernia to Rome on August 22
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
8:50am	Isernia	2h 30m	11:20am	Termini	Cheapest
11:35am	Isernia	2h 25m	2:00pm	Rome Tiburtina Bus Station	Fastest
3:15pm	Isernia	2h 30m	5:45pm	Termini	No tags
11:35am	Isernia	9h 40m	9:15pm	Rome Fiumicino Airport	No tags
6:15pm	Isernia	6h 45m	1:00am	Rome Fiumicino Airport	No tags

Next departures for Isernia to Rome on August 23
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
8:50am	Isernia	2h 30m	11:20am	Termini	Cheapest
11:35am	Isernia	2h 25m	2:00pm	Rome Tiburtina Bus Station	Fastest
3:30pm	Isernia	2h 30m	6:00pm	Termini	No tags
11:35am	Isernia	9h 40m	9:15pm	Rome Fiumicino Airport	No tags
5:35pm	Isernia	2h 30m	8:05pm	Termini	No tags
6:15pm	Isernia	6h 45m	1:00am	Rome Fiumicino Airport	No tags

Next departures for Isernia to Rome on August 24
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
8:50am	Isernia	2h 30m	11:20am	Termini	Cheapest
11:35am	Isernia	2h 25m	2:00pm	Rome Tiburtina Bus Station	Fastest
3:15pm	Isernia	2h 30m	5:45pm	Termini	No tags
11:35am	Isernia	9h 40m	9:15pm	Rome Fiumicino Airport	No tags
3:20pm	Isernia	5h 11m	8:31pm	Termini	No tags
6:15pm	Isernia	6h 45m	1:00am	Rome Fiumicino Airport	No tags

Next departures for Isernia to Rome on August 25
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
8:50am	Isernia	2h 30m	11:20am	Termini	Cheapest
11:35am	Isernia	2h 25m	2:00pm	Rome Tiburtina Bus Station	Fastest
3:15pm	Isernia	2h 30m	5:45pm	Termini	No tags
6:05pm	Isernia	6h 55m	1:00am	Rome Fiumicino Airport	No tags
3:20pm	Isernia	5h 11m	8:31pm	Termini	No tags

Next departures for Isernia to Rome on August 26
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
11:35am	Isernia	2h 25m	2:00pm	Rome Tiburtina Bus Station	CheapestFastest
8:50am	Isernia	2h 30m	11:20am	Termini	No tags
6:05pm	Isernia	6h 55m	1:00am	Rome Fiumicino Airport	No tags
3:15pm	Isernia	2h 30m	5:45pm	Termini	No tags
3:20pm	Isernia	5h 11m	8:31pm	Termini	No tags

Next departures for Isernia to Rome on August 27
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
11:35am	Isernia	2h 25m	2:00pm	Rome Tiburtina Bus Station	CheapestFastest
8:50am	Isernia	2h 30m	11:20am	Termini	No tags
11:45am	Isernia	9h 30m	9:15pm	Rome Fiumicino Airport	No tags
3:15pm	Isernia	2h 30m	5:45pm	Termini	No tags
6:05pm	Isernia	6h 55m	1:00am	Rome Fiumicino Airport	No tags
3:20pm	Isernia	5h 11m	8:31pm	Termini	No tags

Last refresh of the prices: Yesterday at 11:26 PM CEST.

Compare 2 ways to go from Isernia to Rome

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach Rome. The journey takes about 2 hours 30 minutes and with fares starting at just CA$26, it presents an excellent value for a comfortable ride.

3train per day

2h 30mAverage Duration

92 milesDistance

4kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average PriceCA$20 - CA$144	Average Duration6h 45m	CO₂ emissions 4kg CO₂e
Train	Average PriceCA$26 - CA$31	Average Duration2h 30m	CO₂ emissions 4kg CO₂e

Bus stations and stops in Isernia and Rome

Stops in Isernia

A
Isernia
Piazza della Repubblica, 9, 86170 Isernia IS, Italy
Visit page

Stops in Rome

A
Termini
Piazza dei Cinquecento 1, 00185 Roma RM, Italy
Visit page
B
Rome Tiburtina Bus Station
Largo Guido Mazzoni, 3, 00162 Roma, Italy
Visit page
C
Rome Fiumicino Airport (FCO), Train station
Fiumicino Aeroporto, 00054 Fiumicino RM, Italy
Visit page
D
Roma S. Pietro
Roma S.Pietro, 00165 Roma RM, Italy
Visit page
E
Rome Ciampino Airport
Visit page
F
Roma Trastevere
Roma Trastevere Railway Station, 00152 Roma RM, Italy
Visit page

Compare companies

FlixBus

3.5/515,267 reviews

Staff4.1

Timeliness4.0

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Trenitalia

3.9/569 reviews

Staff4.5

Timeliness4.4

Cleanliness4.7

Wifi2.7

Companies in IT:FlixBus, Trenitalia, BlaBlaCar Bus, Deutsche Bahn, ALSA, FlixTrain, Rede Expressos, RegioJet, Trenitalia, Deutsche Bahn ICE, Sindbad, NS Nederlandse Spoorwegen, MarinoBus, Italo

Frequently asked questions about traveling from Isernia to Rome by bus or train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is a ticket from Isernia to Rome?
The cheapest tickets from Isernia to Rome start from CA$20. The average price for this route is around CA$51. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the ride from Isernia to Rome?
The average trip duration from Isernia to Rome is 4h 37m, covering a distance of 96 miles (154 km). The quickest vehicle can get you there in 2h 7m and is operated by Trenitalia.
Which companies service the Isernia to Rome route?
Several major companies operate on this route with 3 trips available per day, including services from FlixBus, Trenitalia.
What is the earliest and latest departure time from Isernia to Rome?
The earliest trip departs from Isernia to Rome at 7:08am. And the latest trip departs at 6:15pm.
What are the CO₂ emissions for the trip from Isernia to Rome?
A trip from Isernia to Rome generates an estimated 3.8434375000000003 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best company from Isernia to Rome?
According to Busbud customers, the highest-rated company on this route is Trenitalia, with an average rating of 3.9 out of 5 stars based on 69 reviews.
Which company has the best Wi-Fi from Isernia to Rome?
Based on reviews on Busbud, the company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which company has the most timely service from Isernia to Rome?
According to Busbud traveler reviews, the most timely company on this route is Trenitalia, with a punctuality rating of 4.4 out of 5 stars.
Which company has the cleanest vehicles from Isernia to Rome?
According to Busbud traveler reviews, the company with the cleanest vehicles on this route is Trenitalia, with a cleanliness rating of 4.7 out of 5 stars.

Find cheapest prices for buses and trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

08/19

CA$25

08/20

CA$22

Today

CA$25

08/22

CA$25

08/23

CA$25

08/24

CA$25

08/25

CA$25

08/26

CA$20

The cheapest trip from Isernia to Rome was searched and found on Aug 26, 2026 with a price of CA$20

To save money and be sure you have the best seat, it's a good idea to buy your bus and train tickets from Isernia to Rome, as early as possible.

You can expect to pay from CA$20 to CA$145 for a bus or train ticket from Isernia to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at CA$20 which is on 2026-08-26.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.