How much is a ticket from Isernia to Rome?

The cheapest tickets from Isernia to Rome start at $23. The average price for this route is around $49. Busbud recommends booking your tickets in advance for a better chance of getting the lowest possible price.

How long is the ride from Isernia to Rome?

The average trip duration from Isernia to Rome is 4h 40m, covering a distance of 154 km. The quickest vehicle can get you there in 2h 7m and is operated by Trenitalia .

Which companies service the Isernia to Rome route?

Several major companies operate on this route with 3 trips available per day, including services from FlixBus , Trenitalia .

What is the earliest and latest departure time from Isernia to Rome?

The earliest trip from Isernia to Rome departs at 7:08am. And the latest trip departs at 8:35pm.

What are the CO₂ emissions for the trip from Isernia to Rome?

A trip from Isernia to Rome generates an estimated 3.8368625 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.

Which is the best company from Isernia to Rome?

According to Busbud customers, the highest-rated company on this route is Trenitalia , with an average rating of 4.0 out of 5 stars based on 63 reviews.

Which company has the best Wi-Fi from Isernia to Rome?

Based on Busbud reviews, the company Trenitalia has the highest Wi‑Fi rating with a score of 2.8.

Which company has the most on-time service from Isernia to Rome?

According to Busbud traveller reviews, the most punctual company on this route is Trenitalia , with a punctuality rating of 4.7 out of 5 stars.

Which company has the cleanest vehicles from Isernia to Rome?

According to Busbud traveller reviews, the company with the cleanest vehicles on this route is Trenitalia , with a cleanliness rating of 4.7 out of 5 stars.

Bus and Train Isernia to Rome from $21 | Refundable Tickets

Next available departures

Next departures for Isernia to Rome on June 30
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
7:10am	Isernia	3h 8m	10:18am	Termini	Cheapest
8:38am	Isernia	2h 9m	10:47am	Termini	Fastest
3:03pm	Isernia	2h 24m	5:27pm	Termini	No tags
6:15pm	Isernia	6h 45m	1:00am	Rome Fiumicino Airport	No tags
3:20pm	Isernia	5h	8:20pm	Termini	No tags
11:35am	Isernia	2h 25m	2:00pm	Rome Tiburtina Bus Station	No tags
6:00pm	Isernia	2h 25m	8:25pm	Termini	No tags

Next departures for Isernia to Rome on July 1
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
7:10am	Isernia	3h 8m	10:18am	Termini	Cheapest
8:38am	Isernia	2h 9m	10:47am	Termini	Fastest
3:03pm	Isernia	2h 24m	5:27pm	Termini	No tags
6:15pm	Isernia	6h 45m	1:00am	Rome Fiumicino Airport	No tags
3:20pm	Isernia	5h	8:20pm	Termini	No tags
11:35am	Isernia	2h 25m	2:00pm	Rome Tiburtina Bus Station	No tags
6:00pm	Isernia	2h 25m	8:25pm	Termini	No tags

Next departures for Isernia to Rome on July 2
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
11:35am	Isernia	2h 25m	2:00pm	Rome Tiburtina Bus Station	Cheapest
8:38am	Isernia	2h 9m	10:47am	Termini	Fastest
7:10am	Isernia	3h 8m	10:18am	Termini	No tags
11:35am	Isernia	9h 40m	9:15pm	Rome Fiumicino Airport	No tags
3:03pm	Isernia	2h 24m	5:27pm	Termini	No tags
6:15pm	Isernia	6h 45m	1:00am	Rome Fiumicino Airport	No tags
3:20pm	Isernia	5h	8:20pm	Termini	No tags
6:00pm	Isernia	2h 25m	8:25pm	Termini	No tags

Next departures for Isernia to Rome on July 3
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
7:10am	Isernia	3h 8m	10:18am	Termini	Cheapest
8:38am	Isernia	2h 9m	10:47am	Termini	Fastest
3:03pm	Isernia	2h 24m	5:27pm	Termini	No tags
11:35am	Isernia	9h 40m	9:15pm	Rome Fiumicino Airport	No tags
3:20pm	Isernia	5h	8:20pm	Termini	No tags
6:15pm	Isernia	6h 45m	1:00am	Rome Fiumicino Airport	No tags
6:00pm	Isernia	2h 25m	8:25pm	Termini	No tags
11:35am	Isernia	2h 25m	2:00pm	Rome Tiburtina Bus Station	No tags

Next departures for Isernia to Rome on July 4
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
7:08am	Isernia	3h 10m	10:18am	Termini	Cheapest
8:38am	Isernia	2h 9m	10:47am	Termini	Fastest
3:03pm	Isernia	2h 24m	5:27pm	Termini	No tags
11:35am	Isernia	9h 40m	9:15pm	Rome Fiumicino Airport	No tags
3:20pm	Isernia	5h	8:20pm	Termini	No tags
6:15pm	Isernia	6h 45m	1:00am	Rome Fiumicino Airport	No tags
6:00pm	Isernia	2h 25m	8:25pm	Termini	No tags
11:35am	Isernia	2h 25m	2:00pm	Rome Tiburtina Bus Station	No tags

Next departures for Isernia to Rome on July 5
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
8:38am	Isernia	2h 9m	10:47am	Termini	Cheapest
5:27pm	Isernia	2h 7m	7:34pm	Termini	Fastest
3:19pm	Isernia	2h 8m	5:27pm	Termini	No tags
11:35am	Isernia	9h 40m	9:15pm	Rome Fiumicino Airport	No tags
6:15pm	Isernia	6h 45m	1:00am	Rome Fiumicino Airport	No tags
11:35am	Isernia	2h 25m	2:00pm	Rome Tiburtina Bus Station	No tags

Next departures for Isernia to Rome on July 6
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
7:08am	Isernia	3h 10m	10:18am	Termini	Cheapest
8:38am	Isernia	2h 14m	10:52am	Termini	Fastest
3:03pm	Isernia	2h 31m	5:34pm	Termini	No tags
11:35am	Isernia	9h 40m	9:15pm	Rome Fiumicino Airport	No tags
3:20pm	Isernia	5h	8:20pm	Termini	No tags
6:15pm	Isernia	6h 45m	1:00am	Rome Fiumicino Airport	No tags
4:45pm	Isernia	5h 3m	9:48pm	Termini	No tags
11:35am	Isernia	2h 25m	2:00pm	Rome Tiburtina Bus Station	No tags

Last refresh of the prices: Yesterday at 11:56 AM CEST.

Compare 2 ways to go from Isernia to Rome

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach Rome. The journey takes about 2 hours 25 minutes, and with fares starting at just $27, it presents an excellent value for a comfortable ride.

4train per day

2h 25mAverage Duration

148 kmDistance

4kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$23 - $195	Average Duration6h 55m	CO₂ emissions 4kg CO₂e
Train	Average Price$27 - $39	Average Duration2h 25m	CO₂ emissions 4kg CO₂e

Where are the popular stops in Isernia and Rome?

Stops in Isernia

A
Isernia
Piazza della Repubblica, 9, 86170 Isernia IS, Italy
Visit page

Stops in Rome

A
Termini
Piazza dei Cinquecento 1, 00185 Roma RM, Italy
Visit page
B
Rome Tiburtina Bus Station
Largo Guido Mazzoni, 3, 00162 Roma, Italy
Visit page
C
Rome Fiumicino Airport (FCO), Train station
Fiumicino Aeroporto, 00054 Fiumicino RM, Italy
Visit page
D
Roma S. Pietro
Roma S.Pietro, 00165 Roma RM, Italy
Visit page
E
Roma Trastevere
Roma Trastevere Railway Station, 00152 Roma RM, Italy
Visit page
F
Rome Ciampino Airport
Visit page

Compare companies

FlixBus

3.5/512,930 reviews

Staff4.2

Timeliness4.0

Cleanliness4.1

Wi‑Fi2.7

Trenitalia

4.0/564 reviews

Staff4.7

Timeliness4.7

Cleanliness4.7

Wi‑Fi2.8

Companies in IT:FlixBus, Trenitalia, BlaBlaCar Bus, Deutsche Bahn, ALSA, FlixTrain, Rede Expressos, RegioJet, Trenitalia, Deutsche Bahn ICE, Sindbad, NS Nederlandse Spoorwegen, MarinoBus, Italo

Frequently asked questions about travelling from Isernia to Rome by bus or train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is a ticket from Isernia to Rome?
The cheapest tickets from Isernia to Rome start at $23. The average price for this route is around $49. Busbud recommends booking your tickets in advance for a better chance of getting the lowest possible price.
How long is the ride from Isernia to Rome?
The average trip duration from Isernia to Rome is 4h 40m, covering a distance of 154 km. The quickest vehicle can get you there in 2h 7m and is operated by Trenitalia.
Which companies service the Isernia to Rome route?
Several major companies operate on this route with 3 trips available per day, including services from FlixBus, Trenitalia.
What is the earliest and latest departure time from Isernia to Rome?
The earliest trip from Isernia to Rome departs at 7:08am. And the latest trip departs at 8:35pm.
What are the CO₂ emissions for the trip from Isernia to Rome?
A trip from Isernia to Rome generates an estimated 3.8368625 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best company from Isernia to Rome?
According to Busbud customers, the highest-rated company on this route is Trenitalia, with an average rating of 4.0 out of 5 stars based on 63 reviews.
Which company has the best Wi-Fi from Isernia to Rome?
Based on Busbud reviews, the company Trenitalia has the highest Wi‑Fi rating with a score of 2.8.
Which company has the most on-time service from Isernia to Rome?
According to Busbud traveller reviews, the most punctual company on this route is Trenitalia, with a punctuality rating of 4.7 out of 5 stars.
Which company has the cleanest vehicles from Isernia to Rome?
According to Busbud traveller reviews, the company with the cleanest vehicles on this route is Trenitalia, with a cleanliness rating of 4.7 out of 5 stars.

Find the cheapest prices for buses and trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

06-28

$25

06-29

$25

Today

$25

07-01

$25

07-02

$24

07-03

$25

07-04

$25

07-05

$25

The cheapest trip from Isernia to Rome was searched and found on Jul 2, 2026 with a price of $24

To save money and make sure you have the best seat, it's a good idea to buy your bus and train tickets from Isernia to Rome, as early as possible.

You can expect to pay between $24 and $92 for a bus or train ticket from Isernia to Rome based on the past 2 days. You can expect to find the lowest price for this trip at $24 on 2026-07-02.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.